10% of women who vitrified their oocytes for social reasons used them

10% of women who vitrified their oocytes for social reasons used them

The preservation of fertility due to the desire to postpone motherhood is an option that more and more women turn to, although it is a strategy that is rarely talked about. In our country it has grown, especially in the last five years. It is difficult to obtain conclusive data regarding the use of gametes or embryos preserved for this purpose since most of these treatments was carried out a few years ago. However, a team of the Reproductive Medicine Service of the Dexeus Mujer centre carried out a study that allows us to extract some useful information.

The work has been led by biologist Clara González, and it is a retrospective follow-up study of patients who vitrified their oocytes between 2009 and 2017. Of the total, 10% of the patients (342) decided to use them later in that period.

Of the 342 patients who vitrified oocytes, 13.2% (45/342) came to discuss about reproductive desire in the studied period. 9.6% (33/342) of them initiated a cycle of oocyte cryotransfer and subsequent IVF. The average age of these women was 40.9 ± 2.5 years. The ovocitary survival rate was 84.5% (284/336). After performing an IVF cycle and transferring an average of 1.4 embryos, 45.5% (15/33) of the women became pregnant after the first attempt. 26.7% (4/15) had a miscarriage. 63.6% (21/33) of the patients vitrified leftover embryos. 9 cryotransfers were performed and resulted in 6 gestations, which gave a cumulative pregnancy rate of 60.6% (20/33).

5.8% (20/342) of the women who had vitrified oocytes preferred alternative techniques (IVF, Artificial Insemination) rather than using said vitrified oocytes. The pregnancy rate per IVF cycle was 38.4% (5/13). 6.2% (18/290) got pregnant spontaneously and still maintain their vitrified oocytes. A woman decided to destroy the cryopreserved oocytes.

According to the authors, fertility preservation offers adequate results, consistent with the age when oocytes are vitrified, therefore it is important to report on this aspect, in order for vitrification to be done in the period that allows greater chances of success.

Reference work:

Poster: Non-medical fertility preservation: eight years of follow-up

González Llagostera C., Solé Inarejos M., Devesa Rodríguez de la Rúa M., Boada Palá M., Barri Ragué PN., Veiga Lluch A.
Reproduction Medicine Service. Obstetrics, Gynaecology and Reproduction Department. Hospital Universitario Dexeus. Barcelona.

32nd National Congress of the Spanish Fertility Society (SEF), Madrid, 2018